Lab-in-the-Loop at Compute Speed — Ian Quigley, Leash Bio
How Leash Bio tamed DELs, the assay that traumatizes everyone, and used the data to catch cheating models. And why that same data is perfect for AI agents learning to think like chemists.
#Data and training
#Data and training
0 todayOct 15
Researchers use AI to design proteins that cut up other proteins
AI design tools make proteins that break bonds that are stable for hundreds of years.
HiRO-ACEv2: Simulating extreme weather at 3 km resolution for a fraction of the cost
🤗 Models | 📄 Paper | 📓 Tutorial notebooks | 🌎 Demo We introduce HiRO-ACEv2, the newest update to our High Resolution Output Ai2 Climate Emulator (HiRO-ACE) system.
Microsoft has a new machine learning tool to improve weather forecasts
Old-school physics-based weather forecasting and even new AI models typically become less reliable beyond two weeks, a problem Microsoft claims to have solved using machine learning.
Oct 14
Scimplify raises $25M to challenge China’s grip on critical materials with AI
Scimplify's annualized revenue run rate has tripled to $200 million as it eyes U.S. expansion.
Industrial Next wants factory robots to switch tasks in minutes, not weeks
Industrial Next helps manufacturers automate complex, delicate tasks that have traditionally required human labor.
Dyna-2: General Purpose Physical Agents with Hour-Long Autonomy — Jason Ma, Dyna Robotics
Our first robotics pod with Dyna’s Chief Scientist on their big bet on World Action Models & the Next Frontier of Physical AI
Laplace Intelligence red-teams robots and self-driving cars before they hit the real world
University of Michigan spinout Laplace Intelligence uses AI agents and interactive simulation to stress-test robots and self-driving vehicles before deployment. The profitable startup is competing at TechCrunch Disrupt's Startup Battlefield.
Oct 13
AI labs are buying data from dead startups to train their models
When Keelan Miskell began winding down his crypto startup this year, he didn’t think its data was worth much: the users were anonymous, the company just a few years old. But he’s since turned the firm’s digital archives into real money.
Sakana AI's self-improving model gets better at solving and judging, but can't catch its own blind spots
Sakana AI's MASS method lets one language model improve itself by solving tasks, judging results, and refining workflows, reaching a win rate of nearly 70 percent against the base model after two rounds. But when the model misses the same errors across all three roles, it can mistake them for progress and reinforce them during training.
Simulating student learning for better AI tutoring
StudentSim is a research system for evaluating and improving AI tutoring tools before they are tested with learners. It models how individuals may engage with tutors, giving feedback to improve tutor performance across subjects like chess, writing, and mathematics.
WindBorne wins a hefty US Air Force contract for its balloon data
A Silicon Valley startup that uses weather balloons and AI to predict the weather won a U.S. military contract worth almost $50 million.
Meta releases its first frontier model, Muse Wonder
Meta's Superintelligence Lab released a pair of new state-of-the-art models on Monday, Muse Wonder and Muse Wonder Full, the company's first attempt at a frontier model.
Oct 11
AI agents overstate their results and remain far from autonomous research, study finds
Epoch AI and Anthropic independently found the same thing: current AI models like GPT-5.6 Sol and Claude Fable 5 can run experiments but lack scientific self-criticism and genuine creative thinking. At best, Sol reached 15 percent of the human reference score, and even that came from methods researchers already knew.
Oct 10
Building AI for Reliable Execution: Lessons From Industrial Robotics
Inside Standard Bots’ AI stack, pretrained models learn factory tasks from demonstrations and improve through corrections from real deployments.
Why AlphaFold Didn't Solve Protein Folding — Pushmeet Kohli, Google DeepMind & Sal Candido, Biohub
From the Bitter Lesson of AI scaling to the unsolved mysteries of protein folding, Google DeepMind’s Pushmeet Kohli and Biohub’s Sal Candido are rethinking what it takes to build AI that truly understands biology.
‘Pure insanity’: Mathematicians will need years to make sense of OpenAI’s latest drop
"Staggering." "Overwhelming." "Unprecedented." "Surreal." "Pure insanity." Those were among the descriptions more than three dozen mathematicians reached for in conversations with The Verge as they tried to make sense of the flood of mathematical results OpenAI abruptly dropped on the field this week.
The maker of non-text AI model Jev valued at $7.5B just weeks after launch
What has users and large corporations so excited about Jev is TypeSafe’s claim that it works significantly faster and uses far fewer tokens than LLMs.
Oct 9
Claude can now generate animated explainer videos and live data dashboards from text prompts
Anthropic launched two new beta features for Claude. Dashboards turns data sources like BigQuery and Snowflake into live dashboards from text prompts. Motion generates animated explainer videos from text and images. Docs, Slides, and Design now work across all plans, including free accounts.
Synthesis Superintelligence: from Semiconductors to Superconductors — Periodic Labs’ Liam Fedus and Ekin Dogus Cubuk
A special Science pod and Engineering pod crossover.. with Forward Deployed Engineering kicker!
Share GPU clusters across teams with isolation and fairness using Amazon SageMaker HyperPod
A reference architecture for securely sharing one Amazon SageMaker HyperPod EKS cluster across multiple teams, using AWS IAM Identity Center for authentication, per-team SageMaker Domains and Kubernetes namespaces for isolation, HyperPod Task Governance for fairness, and namespace-level cost allocation for chargeback.
Ben Affleck is an AI nerd, and the internet is impressed
Ben Affleck is going viral for his deep knowledge of AI, from neural networks and transformers to open weights. The actor, who sold his AI filmmaking startup to Netflix earlier this year, is proving he's more than just a Hollywood star.
Oct 8
Agent Lightning v1.0: A 3,500-Line Lightweight Agentic RL Framework for Training Agents with Real Harnesses
Training AI agents with reinforcement learning can be challenging because their tools, context, and decision-making are managed by complex frameworks. Agent Lightning connects existing agents to RL training, making it easier to improve them without rebuilding them.
Zuckerberg's Biohub leads a $1.8 billion push to build AI models that predict cell behavior
Biohub, the research organization backed by Mark Zuckerberg and Priscilla Chan, is coordinating a $1.8 billion initiative to train AI models that predict cell behavior. Meta, Google DeepMind, Isomorphic Labs, and the US Department of Energy are funding data, lab equipment, and compute. A first dataset should be ready in about a year.
Oct 7
Google invests millions in Mark Zuckerberg’s efforts to create a ‘virtual cell’
Google DeepMind, Meta, and AI drug discovery startup Isomorphic Labs are jointly investing $300 million into Biohub, the nonprofit biomedical research organization founded by Mark Zuckerberg and his wife, Priscilla Chan, as reported by Reuters.
Healthleap raises $38M for its AI that flags hospital patients who may need a closer look
The financing includes an $8M seed round co-led by Sequoia Capital and First Round Capital, and a $30 million Series A led by Hummingbird Ventures.
One Model Family, Two Gold-Level Results: Fine-Tuning Nemotron for IOI and IMO
The International Olympiad in Informatics (IOI) and the International Mathematical Olympiad (IMO) test different skills. IOI requires algorithms and code that pass hidden tests under strict time and submission limits. IMO demands rigorous natural-language proofs.
[AINews] Quasi-Riemann-Hypothesis: OpenAI publishes 722 math papers solving 90 of the top 500 open math problems; “the most significant moment” in >100 years of mathematics
The release : OpenAI published a broad set of mathematical results from an internal frontier model in a public GitHub repo .
Sharing AI progress in mathematics
OpenAI publishes new results on open problems in mathematics from an internal frontier model and shares Lean proof formalizations and research details on GitHub.
How Jump Trading is scaling quant research with ChatGPT
Jump Trading uses OpenAI to expand quantitative research. See how longer-running AI workflows combine multiple data sources with human review.
OpenAI drops another batch of mathematical breakthroughs
OpenAI has revealed solutions to a number of long-standing mathematics problems produced by an unreleased frontier model in a batch of 722 manuscripts, covering 372 result families that group related papers.
Introducing Mistral Large 4: Le chonk
Introducing Mistral Large 4: Le chonk Mistral are back in the game. Today they're releasing a preview of Mistral Large 4, a 1 trillion parameter, 49 billion active parameter model trained on their own cluster of 3,800 NVIDIA Grace Blackwell GPUs. The preview is available via their API.
Best practices for Amazon SageMaker HyperPod administration and governance
Learn how to administer Amazon SageMaker HyperPod through Amazon SageMaker Unified Studio while preserving cluster governance. This post shows platform teams how to design infrastructure boundaries, govern access, allocate shared capacity, and operate HyperPod consistently across the organization, project, cluster, and workload control layers.
Mirror Particle is building a ‘world model’ of human behavior
Mirror Particle will launch at TechCrunch Disrupt's Startup Battlefield 200 with a world model built from scratch to predict human behavior, arguing that LLM role-play falls short for market research and brand strategy.
Oct 6
Unlocking Earth AI’s planetary geospatial foundation models for global public health
Public health decisions rely heavily on timely, granular data. For health conditions, such as cardiovascular disease or postpartum depression, that data shows us where to focus resources and support. For acute disease outbreaks, such as dengue or cholera, it can help inform urgent operational protocols and resource allocation.
Mistral’s new 1T model aims to leapfrog closed and open rivals
French AI lab Mistral AI has released Mistral Large 4, a new large multimodal model aiming to leapfrog both American and Chinese rivals.
Researchers stretch LeCun's JEPA AI into a universal world model that works from physics to biology
Researchers at PhAI Labs have expanded Yann LeCun's JEPA architecture to work across seven fields, from robotics to biomedicine. The effort also produced a liver cancer treatment candidate that showed promise in lab tests, though the study doesn't establish whether it could become an actual therapy.
CATL and Tencent back Deepseek's ballooning funding round as the AI startup eyes a 2027 IPO
Deepseek is close to raising at least $12 billion in a new funding round, Bloomberg reports.
Falcon-Emirati: When an LLM Learns the Dialect, the Culture, and the Nuance
Try Falcon Emirati → Arabic is really a family of languages living under one name. Modern Standard Arabic is what you read in the news or a textbook, but it's rarely how people actually talk to each other.
[AINews] Reflection Beam - 501B-A23B American Open Model
Reflection announced Beam, a text-only 501B-total / 23B-active MoE for coding, agentic and scientific work. It was trained from scratch, and full weights under Apache 2.0 are due this month.